Sarcosine is a prostate epigenetic modifier that elicits aberrant methylation patterns through the SAMe‐Dnmts axis

DNA hypermethylation is one of the most common epigenetic modifications in prostate cancer (PCa). Several studies have delineated sarcosine as a PCa oncometabolite that increases the migration of malignant prostate cells while decreasing their doubling time. Here, we show that incubation of prostate...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Strmiska, Vladislav, Michalek, Petr, Lackova, Zuzana, Guran, Roman, Krizkova, Sona, Vanickova, Lucie, Zitka, Ondrej, Stiborova, Marie, Eckschlager, Tomas, Klejdus, Borivoj, Pacik, Dalibor, Tvrdikova, Eliska, Keil, Claudia, Haase, Hajo, Adam, Vojtech, Heger, Zbynek
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487735/
https://ncbi.nlm.nih.gov/pubmed/30628163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12439
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