Osteopontin attenuates inflammation via JAK2/STAT1 pathway in hyperglycemic rats after intracerebral hemorrhage

Acute intracerebral hemorrhage (ICH) complicated by hyperglycemia is associated with aggravation of post-stroke inflammation, leading to exacerbation of brain edema and predicting poor neurological outcomes and higher mortality of patients. Osteopontin (OPN) is a neuroprotective glycoprotein, which...

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Vydáno v:Neuropharmacology
Hlavní autoři: Gong, Lei, Manaenko, Anatol, Fan, Ruiming, Huang, Lei, Enkhjargal, Budbazar, McBride, DevinW., Ding, Yan, Tang, Jiping, Xiao, Xiaoqiu, Zhang, John H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487497/
https://ncbi.nlm.nih.gov/pubmed/29885817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.06.009
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