N-Terminal Domain of Fragile Histidine Triad Exerts Potent Cytotoxic Effect in HT1080 Cells and Increases Doxorubicin Cytotoxicity

Fragile histidine triad (FHIT) serves a critical function as a tumor suppressor that inhibits p53 degradation by mouse double minute 2 (MDM2). The functional domains of FHIT involved in tumor inhibition was interpreted. In-silico screening data were employed to construct truncated forms of FHIT to a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Iran J Pharm Res
Egile Nagusiak: Eslamparast, Ameneh, Abbasgholizadeh, Reza, Ostad, Seyed Nasser, Gharghabi, Mehdi, Ghahremani, Mohammad Hossein
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Shaheed Beheshti University of Medical Sciences 2019
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487436/
https://ncbi.nlm.nih.gov/pubmed/31089360
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak