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Design and Construction of a Novel Humanized Single-Chain Variable-Fragment Antibody Against the Tumor Necrosis Factor Alpha

The pro-inflammatory cytokine, TNF-α, which plays a major role in the development and persistence of diseases such as Crohn’s disease, psoriasis, psoriatic arthritis, and rheumatoid arthritis, is the basis for the use of anti-TNF-α therapies. The neutralization of TNF-α or blockage of its binding to...

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Foilsithe in:Iran J Pharm Res
Main Authors: Farajzadeh, Davoud, Karimi-Gharigh, Sadigheh, Jalali-Kondori, Parisa, Dastmalchi, Siavoush
Formáid: Artigo
Teanga:Inglês
Foilsithe: Shaheed Beheshti University of Medical Sciences 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487432/
https://ncbi.nlm.nih.gov/pubmed/31089365
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