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An Investigation into the Role of P-Glycoprotein in the Intestinal Absorption of Repaglinide: Assessed by Everted Gut Sac and Caco-2 Cell Line

The present study aimed at exploring the potential of the P-glycoprotein (P-gp) transporters as a barrier to the repaglinide (REG) epithelial permeability. In-vitro intestinal absorption models, the everted gut sac, and Caco-2 cell line, were used to study the possible role of P-gp in intestinal tra...

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Bibliografiske detaljer
Udgivet i:Iran J Pharm Res
Main Authors: Yaghoobian, Morteza, Haeri, Azadeh, Bolourchian, Noushin, Shahhosseini, Soraya, Dadashzadeh, Simin
Format: Artigo
Sprog:Inglês
Udgivet: Shaheed Beheshti University of Medical Sciences 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487404/
https://ncbi.nlm.nih.gov/pubmed/31089348
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