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Validation of a cell-based colorimetric reporter gene assay for the evaluation of Type I Interferons

The biotherapeutic type I interferons (IFN-I) are indicated to treat several diseases. These products are regulated to guarantee safety and efficacy through critical quality attributes. For this purpose, the development of robust assays is required, followed by its validation to demonstrate their su...

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Detalhes bibliográficos
Publicado no:Biotechnol Rep (Amst)
Main Authors: Mejía-Calvo, Ignacio, Muñoz-García, Leslie, Jiménez-Uribe, Alexis, Camacho-Sandoval, Rosa, González-González, Edith, Mellado-Sánchez, Gabriela, Tenorio-Calvo, Alejandra V., López-Morales, Carlos A., Velasco-Velázquez, Marco A., Pavón, Lenin, Pérez-Tapia, Sonia Mayra, Medina-Rivero, Emilio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487280/
https://ncbi.nlm.nih.gov/pubmed/31061815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2019.e00331
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