Melatonin Increases Bone Mass around the Prostheses of OVX Rats by Ameliorating Mitochondrial Oxidative Stress via the SIRT3/SOD2 Signaling Pathway

Bone mass loss around prostheses is a major cause of implant failure, especially in postmenopausal osteoporosis patients. In osteoporosis, excess oxidative stress largely contributed abnormal bone remodeling. Melatonin, which is synthesized from the pineal gland, promotes osteoblast differentiation...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Zhou, Wei, Liu, Yu, Shen, Jining, Yu, Binqing, Bai, Jiaxiang, Lin, Jiayi, Guo, Xiaobin, Sun, Houyi, Chen, Zhanghuan, Yang, Huilin, Xu, Yaozeng, Geng, Dechun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487111/
https://ncbi.nlm.nih.gov/pubmed/31110599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4019619
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