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Immunoglobulin G responses against falciparum malaria specific antigens are higher in children with homozygous sickle cell trait than those with normal hemoglobin

BACKGROUND: High Immunoglobulin G (IgG) response to Plasmodium falciparum antigens is associated with partial malaria protection in sickle hemoglobin (HbS) children. However, this response has been more studied in children with heterozygous sickle cell trait (HbAS) but little explored in those with...

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Bibliographic Details
Published in:BMC Immunol
Main Authors: Bwire, George Msema, Majigo, Mtebe, Makalla, Robert, Nkinda, Lillian, Mawazo, Akili, Mizinduko, Mucho, Makani, Julie
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486967/
https://ncbi.nlm.nih.gov/pubmed/31029083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-019-0294-z
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