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Differential expression of human tRNA genes drives the abundance of tRNA-derived fragments

The human genome encodes hundreds of transfer RNA (tRNA) genes but their individual contribution to the tRNA pool is not fully understood. Deep sequencing of tRNA transcripts (tRNA-Seq) can estimate tRNA abundance at single gene resolution, but tRNA structures and posttranscriptional modifications i...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Torres, Adrian Gabriel, Reina, Oscar, Stephan-Otto Attolini, Camille, Ribas de Pouplana, Lluís
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486751/
https://ncbi.nlm.nih.gov/pubmed/30962382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821120116
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