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TePhe, a tellurium-containing phenylalanine mimic, allows monitoring of protein synthesis in vivo with mass cytometry

Protein synthesis is central to maintaining cellular homeostasis and its study is critical to understanding the function and dysfunction of eukaryotic systems. Here we report L-2-tellurienylalanine (TePhe) as a noncanonical amino acid for direct measurement of protein synthesis. TePhe is synthetical...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bassan, Jay, Willis, Lisa M., Vellanki, Ravi N., Nguyen, Alan, Edgar, Landon J., Wouters, Bradly G., Nitz, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486722/
https://ncbi.nlm.nih.gov/pubmed/30971489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821151116
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