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Effects on prostate cancer cells of targeting RNA polymerase III

RNA polymerase (pol) III occurs in two forms, containing either the POLR3G subunit or the related paralogue POLR3GL. Whereas POLR3GL is ubiquitous, POLR3G is enriched in undifferentiated cells. Depletion of POLR3G selectively triggers proliferative arrest and differentiation of prostate cancer cells...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Petrie, John L, Swan, Caroline, Ingram, Richard M, Frame, Fiona M, Collins, Anne T, Dumay-Odelot, Hélène, Teichmann, Martin, Maitland, Norman J, White, Robert J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486637/
https://ncbi.nlm.nih.gov/pubmed/30820548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz128
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