Density of σ70 promoter-like sites in the intergenic regions dictates the redistribution of RNA polymerase during osmotic stress in Escherichia coli

RNA polymerase (RNAP), the transcription machinery, shows dynamic binding across the genomic DNA under different growth conditions. The genomic features that selectively redistribute the limited RNAP molecules to dictate genome-wide transcription in response to environmental cues remain largely unkn...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Sun, Zhe, Cagliero, Cedric, Izard, Jerome, Chen, Yixiong, Zhou, Yan Ning, Heinz, William F, Schneider, Thomas D, Jin, Ding Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486629/
https://ncbi.nlm.nih.gov/pubmed/30843055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz159
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