A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice

Toll-like receptors (TLRs) recognize pathogen/damage-associated molecular patterns and initiate inflammatory signaling cascades. Occasionally, overexpression of TLRs leads to the onset of numerous inflammatory diseases, necessitating the development of selective inhibitors to allow a protective yet...

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Publicado no:Exp Mol Med
Main Authors: Kwon, Hyuk-Kwon, Patra, Mahesh Chandra, Shin, Hyeon-Jun, Gui, Xiangai, Achek, Asma, Panneerselvam, Suresh, Kim, Dong-Jin, Song, Suk-Jong, Hong, Riwon, Kim, Kyoung Soo, Kim, Yang Gyun, Lee, Francis Y., Hahm, Dae-Hyun, Lee, Sang Ho, Choi, Sangdun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486608/
https://ncbi.nlm.nih.gov/pubmed/31028244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0244-0
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