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Rbfox2 dissociation from stress granules suppresses cancer progression

Stress granules (SGs) are stalled translation initiation complexes comprising untranslated mRNAs and RNA-binding proteins (RBPs). RBP fox-1 homolog 2 (Rbfox2), a component of SGs, binds to retinoblastoma 1 (RB1) mRNA, which is closely related to cancer progression; however, the role of Rbfox2 in can...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Choi, Sunkyung, Sa, Moa, Cho, Namjoon, Kim, Kee K., Park, Su-Hyung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486603/
https://ncbi.nlm.nih.gov/pubmed/31028247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0246-y
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