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The subthreshold-active K(V)7 current regulates neurotransmission by limiting spike-induced Ca(2+) influx in hippocampal mossy fiber synaptic terminals

Little is known about the properties and function of ion channels that affect synaptic terminal-resting properties. One particular subthreshold-active ion channel, the Kv7 potassium channel, is highly localized to axons, but its role in regulating synaptic terminal intrinsic excitability and release...

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Pubblicato in:Commun Biol
Autori principali: Martinello, Katiuscia, Giacalone, Elisabetta, Migliore, Michele, Brown, David A., Shah, Mala M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486593/
https://ncbi.nlm.nih.gov/pubmed/31044170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0408-4
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