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Binless normalization of Hi-C data provides significant interaction and difference detection independent of resolution
Chromosome conformation capture techniques, such as Hi-C, are fundamental in characterizing genome organization. These methods have revealed several genomic features, such as chromatin loops, whose disruption can have dramatic effects in gene regulation. Unfortunately, their detection is difficult;...
Zapisane w:
| Wydane w: | Nat Commun |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486590/ https://ncbi.nlm.nih.gov/pubmed/31028255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09907-2 |
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