Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless

Maleless (MLE) is an evolutionary conserved member of the DExH family of helicases in Drosophila. Besides its function in RNA editing and presumably siRNA processing, MLE is best known for its role in remodelling non-coding roX RNA in the context of X chromosome dosage compensation in male flies. ML...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Ankush Jagtap, Pravin Kumar, Müller, Marisa, Masiewicz, Pawel, von Bülow, Sören, Hollmann, Nele Merret, Chen, Po-Chia, Simon, Bernd, Thomae, Andreas W, Becker, Peter B, Hennig, Janosch
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486548/
https://ncbi.nlm.nih.gov/pubmed/30805612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz125
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