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Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins
Poly(ADP-ribosyl)ation (PARylation) is posttranslational modification of proteins by linear or branched chains of ADP-ribose units, originating from NAD+. The central enzyme for PAR production in cells and the main target of poly(ADP-ribosyl)ation during DNA damage is poly(ADP-ribose) polymerase 1 (...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486540/ https://ncbi.nlm.nih.gov/pubmed/30799503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz120 |
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