Diagnosis of known sarcoma fusions and novel fusion partners by targeted RNA sequencing with identification of a recurrent ACTB-FOSB fusion in pseudomyogenic hemangioendothelioma

Integration of morphological, immunohistochemical and molecular methods is often necessary for the precise diagnosis and optimal clinical management of sarcomas. We have validated and implemented a clinical molecular diagnostic assay, MSK-Fusion Solid, for detection of gene fusions in solid tumors i...

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Veröffentlicht in:Mod Pathol
Hauptverfasser: Zhu, Guo, Benayed, Ryma, Ho, Caleb, Mullaney, Kerry, Sukhadia, Purvil, Rios, Kelly, Berry, Ryan, Rubin, Brian P., Nafa, Khedoudja, Wang, Lu, Klimstra, David S., Ladanyi, Marc, Hameed, Meera R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486453/
https://ncbi.nlm.nih.gov/pubmed/30459475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41379-018-0175-7
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