Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis

T cell heterogeneity is highly relevant to allergic disorders. We resolved the heterogeneity of human tissue CD3(+) T cells during allergic inflammation, focusing on a tissue-specific allergic disease, eosinophilic esophagitis (EoE). We investigated 1088 single T cells derived from patients with a s...

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Vydáno v:J Clin Invest
Hlavní autoři: Wen, Ting, Aronow, Bruce J., Rochman, Yrina, Rochman, Mark, KC, Kiran, Dexheimer, Phil J., Putnam, Philip, Mukkada, Vincent, Foote, Heather, Rehn, Kira, Darko, Sam, Douek, Daniel, Rothenberg, Marc E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486341/
https://ncbi.nlm.nih.gov/pubmed/30958799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125917
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