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Setting traps for NKG2A gives NK cell immunotherapy a fighting chance

The equilibrium of signaling through activating and inhibitory receptors dictates whether a given NK cell will execute cellular cytotoxicity. In this issue of the JCI, Kamiya et al. describe a novel approach to efficiently inhibiting surface expression of the inhibitory receptor CD94/NK group 2 memb...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Cichocki, Frank, Miller, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486336/
https://ncbi.nlm.nih.gov/pubmed/30985296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128480
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