Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis

Pulmonary fibrosis (PF) is an intractable disorder with a poor prognosis. Although lung fibroblasts play a central role in PF, the key regulatory molecules involved in this process remain unknown. To address this issue, we performed a time-course transcriptome analysis on lung fibroblasts of bleomyc...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Shichino, Shigeyuki, Ueha, Satoshi, Hashimoto, Shinichi, Otsuji, Mikiya, Abe, Jun, Tsukui, Tatsuya, Deshimaru, Shungo, Nakajima, Takuya, Kosugi-Kanaya, Mizuha, Shand, Francis H.W., Inagaki, Yutaka, Shimano, Hitoshi, Matsushima, Kouji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485671/
https://ncbi.nlm.nih.gov/pubmed/30626759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122163
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