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Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events

Adjuvanted vaccines afford invaluable protection against disease, while the molecular and cellular changes they induce offer direct insight into human immunobiology. Here we show that within 24 hours of receiving adjuvanted swine flu vaccine, healthy individuals made expansive, complex molecular and...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Sobolev, Olga, Binda, Elisa, O’Farrell, Sean, Lorenc, Anna, Pradines, Joel, Huang, Yongqing, Duffner, Jay, Schulz, Reiner, Cason, John, Zambon, Maria, Malim, Michael H., Peakman, Mark, Cope, Andrew, Capila, Ishan, Kaundinya, Ganesh V., Hayday, Adrian C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485475/
https://ncbi.nlm.nih.gov/pubmed/26726811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3328
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