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Non-invasive detection of HER2 amplification with plasma DNA Digital PCR

PURPOSE: Digital PCR is a highly accurate method of determining DNA concentration. We adapted digital PCR to determine the presence of oncogenic amplification through non-invasive analysis of circulating free plasma DNA, and exemplify this approach by developing a plasma DNA digital PCR assay for HE...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Gevensleben, Heidrun, Garcia-Murillas, Isaac, Graeser, Monika K, Schiavon, Gaia, Osin, Peter, Parton, Marina, Smith, Ian E, Ashworth, Alan, Turner, Nicholas C
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485473/
https://ncbi.nlm.nih.gov/pubmed/23637122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3768
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