Site-selective installation of BASHY fluorescent dyes to Annexin V for targeted detection of apoptotic cells

Fluorophores are indispensable for imaging biological processes. We report the design and synthesis of azide-tagged boronic acid salicylidenehydrazone (BASHY) dyes and their use for site-selective labelling of Annexin V. The Annexin V-BASHY conjugate maintaned function and fluorescence as demonstart...

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Publicado en:Chem Commun (Camb)
Main Authors: Cal, Pedro M. S. D., Sieglitz, Florian, Santos, Fábio M. F., Carvalho, Cátia P., Guerreiro, Ana, Bertoldo, Jean B., Pischel, Uwe, Gois, Pedro M. P., Bernardes, Gonçalo J. L.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485347/
https://ncbi.nlm.nih.gov/pubmed/27935613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc08671c
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