SarcTrack: An Adaptable Software Tool for Efficient Large-Scale Analysis of Sarcomere Function in hiPSC-Cardiomyocytes

RATIONALE: Human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs) in combination with CRISPR/Cas9 genome editing provide unparalleled opportunities to study cardiac biology and disease. However, sarcomeres, the fundamental units of myocyte contraction, are immature and nonlinear in h...

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發表在:Circ Res
Main Authors: Toepfer, Christopher N., Sharma, Arun, Cicconet, Marcelo, Garfinkel, Amanda C., Mücke, Michael, Neyazi, Meraj, Willcox, Jon A.L., Agarwal, Radhika, Schmid, Manuel, Rao, Jyoti, Ewoldt, Jourdan, Pourquié, Olivier, Chopra, Anant, Chen, Christopher S., Seidman, Jonathan G., Seidman, Christine E.
格式: Artigo
語言:Inglês
出版: Lippincott Williams & Wilkins 2019
主題:
New Methods in Cardiovascular Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485312/
https://ncbi.nlm.nih.gov/pubmed/30700234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.314505
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