SarcTrack: An Adaptable Software Tool for Efficient Large-Scale Analysis of Sarcomere Function in hiPSC-Cardiomyocytes

RATIONALE: Human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs) in combination with CRISPR/Cas9 genome editing provide unparalleled opportunities to study cardiac biology and disease. However, sarcomeres, the fundamental units of myocyte contraction, are immature and nonlinear in h...

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Опубликовано в: :Circ Res
Главные авторы: Toepfer, Christopher N., Sharma, Arun, Cicconet, Marcelo, Garfinkel, Amanda C., Mücke, Michael, Neyazi, Meraj, Willcox, Jon A.L., Agarwal, Radhika, Schmid, Manuel, Rao, Jyoti, Ewoldt, Jourdan, Pourquié, Olivier, Chopra, Anant, Chen, Christopher S., Seidman, Jonathan G., Seidman, Christine E.
Формат: Artigo
Язык:Inglês
Опубликовано: Lippincott Williams & Wilkins 2019
Предметы:
New Methods in Cardiovascular Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485312/
https://ncbi.nlm.nih.gov/pubmed/30700234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.314505
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