SarcTrack: An Adaptable Software Tool for Efficient Large-Scale Analysis of Sarcomere Function in hiPSC-Cardiomyocytes

RATIONALE: Human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs) in combination with CRISPR/Cas9 genome editing provide unparalleled opportunities to study cardiac biology and disease. However, sarcomeres, the fundamental units of myocyte contraction, are immature and nonlinear in h...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Toepfer, Christopher N., Sharma, Arun, Cicconet, Marcelo, Garfinkel, Amanda C., Mücke, Michael, Neyazi, Meraj, Willcox, Jon A.L., Agarwal, Radhika, Schmid, Manuel, Rao, Jyoti, Ewoldt, Jourdan, Pourquié, Olivier, Chopra, Anant, Chen, Christopher S., Seidman, Jonathan G., Seidman, Christine E.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2019
Assuntos:
New Methods in Cardiovascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485312/
https://ncbi.nlm.nih.gov/pubmed/30700234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.314505
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