Enhanced Performance of Next-Generation Sequencing Diagnostics Compared With Standard of Care Microbiological Diagnostics in Patients Suffering From Septic Shock

OBJECTIVES: Culture-based diagnostics represent the standard of care in septic patients, but are highly insensitive and in many cases unspecific. We recently demonstrated the general feasibility of next-generation sequencing-based diagnostics using free circulating nucleic acids (cell-free DNA) in p...

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Vydáno v:Crit Care Med
Hlavní autoři: Grumaz, Silke, Grumaz, Christian, Vainshtein, Yevhen, Stevens, Philip, Glanz, Karolina, Decker, Sebastian O., Hofer, Stefan, Weigand, Markus A., Brenner, Thorsten, Sohn, Kai
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2019
Témata:
Online Clinical Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485303/
https://ncbi.nlm.nih.gov/pubmed/30720537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000003658
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