Anti-tumor effects and potential therapeutic response biomarkers in α-emitting meta-(211)At-astato-benzylguanidine therapy for malignant pheochromocytoma explored by RNA-sequencing

Targeted α-particle therapy is a promising option for patients with malignant pheochromocytoma. Recent observations regarding meta-(211)At-astato-benzylguanidine ((211)At-MABG) in a pheochromocytoma mouse model showed a strong anti-tumor effect, though the molecular mechanism remains elusive. Here,...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Ohshima, Yasuhiro, Kono, Nobuaki, Yokota, Yuichiro, Watanabe, Shigeki, Sasaki, Ichiro, Ishioka, Noriko S., Sakashita, Tetsuya, Arakawa, Kazuharu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485192/
https://ncbi.nlm.nih.gov/pubmed/31037122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30353
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