Molecular Imaging of Immune Cell Dynamics During De- and Remyelination in the Cuprizone Model of Multiple Sclerosis by [(18)F]DPA-714 PET and MRI

Background: Activation and dysregulation of innate, adaptive and resident immune cells in response to damage determine the pathophysiology of demyelinating disorders. Among the plethora of involved cells, microglia/macrophages and astrocytes play an important role in the pathogenesis of demyelinatin...

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Bibliografische gegevens
Gepubliceerd in:Theranostics
Hoofdauteurs: Zinnhardt, Bastian, Belloy, Michaël, Fricke, Inga B., Orije, Jasmien, Guglielmetti, Caroline, Hermann, Sven, Wagner, Stefan, Schäfers, Michael, Van der Linden, Annemie, Jacobs, Andreas H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2019
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485187/
https://ncbi.nlm.nih.gov/pubmed/31037121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.32461
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