Early Mechanistic Events Induced by Low Molecular Weight Polycyclic Aromatic Hydrocarbons in Mouse Lung Epithelial Cells: A Role for Eicosanoid Signaling

Low molecular weight polycyclic aromatic hydrocarbons (LMW PAHs; < 206.3 g/mol) are under regulated environmental contaminants (eg, secondhand smoke) that lead to gap junction dysregulation, p38 MAPK activation, and increased mRNA production of inflammatory mediators, such as cytokines and cycloo...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Siegrist, Katelyn J, Romo, DeeDee, Upham, Brad L, Armstrong, Michael, Quinn, Kevin, Vanderlinden, Lauren, Osgood, Ross S, Velmurugan, Kalpana, Elie, Marc, Manke, Jonathan, Reinhold, Dominik, Reisdorph, Nichole, Saba, Laura, Bauer, Alison K
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Polyaromatic Hydrocarbons and Eicosanoid Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484882/
https://ncbi.nlm.nih.gov/pubmed/30690640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz030
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