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Genomic Assessment of Blood-Derived Circulating Tumor DNA in Patients With Colorectal Cancers: Correlation With Tissue Sequencing, Therapeutic Response, and Survival

PURPOSE: Genomic alterations in blood-derived circulating tumor DNA (ctDNA) from patients with colorectal cancers were correlated with clinical outcomes. PATIENTS AND METHODS: Next-generation sequencing of ctDNA (54- to 73-gene panel) was performed in 94 patients with colorectal cancer. RESULTS: Mos...

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Pubblicato in:JCO Precis Oncol
Autori principali: Kato, Shumei, Schwaederlé, Maria C., Fanta, Paul T., Okamura, Ryosuke, Leichman, Lawrence, Lippman, Scott M., Lanman, Richard B., Raymond, Victoria M., Talasaz, AmirAli, Kurzrock, Razelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484865/
https://ncbi.nlm.nih.gov/pubmed/31032472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.18.00158
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