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Photoimmunotherapy Targeting Prostate-Specific Membrane Antigen: Are Antibody Fragments as Effective as Antibodies?

Photoimmunotherapy is a highly cell-selective cancer therapy based on an armed antibody conjugate with a phthalocyanine-based photosensitizer, IR700. Photoimmunotherapy induces rapid and highly specific necrosis in targeted cancer cells after exposure to near-infrared (NIR) light. Cells not expressi...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Watanabe, Rira, Hanaoka, Hirofumi, Sato, Kazuhide, Nagaya, Tadanobu, Harada, Toshiko, Mitsunaga, Makoto, Kim, Insook, Paik, Chang H., Wu, Anna M., Choyke, Peter L., Kobayashi, Hisataka
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484861/
https://ncbi.nlm.nih.gov/pubmed/25500827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.114.149526
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