Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylurea: The PIONEER 3 Randomized Clinical Trial

IMPORTANCE: Phase 3 trials have not compared oral semaglutide, a glucagon-like peptide 1 receptor agonist, with other classes of glucose-lowering therapy. OBJECTIVE: To compare efficacy and assess long-term adverse event profiles of once-daily oral semaglutide vs sitagliptin, 100 mg added on to metf...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Rosenstock, Julio, Allison, Dale, Birkenfeld, Andreas L., Blicher, Thalia Marie, Deenadayalan, Srikanth, Jacobsen, Jacob Bonde, Serusclat, Pierre, Violante, Rafael, Watada, Hirotaka, Davies, Melanie
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484814/
https://ncbi.nlm.nih.gov/pubmed/30903796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.2942
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