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Differentiation of monocytes into multinucleated giant bone-resorbing cells: two-step differentiation induced by nurse-like cells and cytokines

Bone resorption in the joints is the characteristic finding in patients with rheumatoid arthritis (RA). Osteoclast-like cells are present in the synovial tissues and invade the bone of patients with RA. The characteristics of these cells are not completely known. In the work reported here, we genera...

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Autors principals: Toyosaki-Maeda, Tomoko, Takano, Hiroshi, Tomita, Tetsuya, Tsuruta, Yuji, Maeda-Tanimura, Miki, Shimaoka, Yasunori, Takahashi, Tetsu, Itoh, Tsunetoshi, Suzuki, Ryuji, Ochi, Takahiro
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC64843/
https://ncbi.nlm.nih.gov/pubmed/11549372
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