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Alzheimer’s Amyloidopathy: An Alternative Aspect

The ‘amyloid hypothesis’ dominates Alzheimer’s disease (AD) research but has failed to deliver effective therapies. Amyloid precursor protein (APP) and presenilin-1 (PSEN1) genetic mutations are undoubtedly pathogenic, albeit by unclear mechanisms. Conversely, high dose B-vitamins convincingly slow...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: Regland, Björn, McCaddon, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484249/
https://ncbi.nlm.nih.gov/pubmed/30814347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-181007
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