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A synthetic non-histone substrate to study substrate targeting by the Gcn5 HAT and sirtuin HDACs

Gcn5 and sirtuins are highly conserved histone acetyltransferase (HAT) and histone deacetylase (HDAC) enzymes that were first characterized as regulators of gene expression. Although histone tails are important substrates of these enzymes, they also target many nonhistone proteins that function in d...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Rössl, Anthony, Denoncourt, Alix, Lin, Mong-Shang, Downey, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484106/
https://ncbi.nlm.nih.gov/pubmed/30804216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006051
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