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Plasma exosomes exacerbate alcohol- and acetaminophen-induced toxicity via CYP2E1 pathway
Cellular CYP2E1 is well-known to mediate alcohol- (ALC) and acetaminophen- (APAP) induced toxicity in hepatic and extra-hepatic cells. Although exosomes have been gaining importance in understanding mechanism of intra- and inter-cellular communication, the functional role of drug metabolizing cytoch...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484097/ https://ncbi.nlm.nih.gov/pubmed/31024054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43064-2 |
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