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The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair
The chromosome 21 encoded protein kinase DYRK1A is essential for normal human development. Mutations in DYRK1A underlie a spectrum of human developmental disorders, and increased dosage in trisomy 21 is implicated in Down syndrome related pathologies. DYRK1A regulates a diverse array of cellular pro...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6483993/ https://ncbi.nlm.nih.gov/pubmed/31024071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42990-5 |
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