Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

Genome-wide association studies have reported 56 independently associated colorectal cancer (CRC) risk variants, most of which are non-coding and believed to exert their effects by modulating gene expression. The computational method PrediXcan uses cis-regulatory variant predictors to impute express...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Hum Genet
Main Authors: Bien, Stephanie A., Su, Yu-Ru, Conti, David V., Harrison, Tabitha A., Qu, Conghui, Guo, Xingyi, Lu, Yingchang, Albanes, Demetrius, Auer, Paul L., Banbury, Barbara L., Berndt, Sonja I., Bézieau, Stéphane, Brenner, Hermann, Buchanan, Daniel D., Caan, Bette J., Campbell, Peter T., Carlson, Christopher S., Chan, Andrew T., Chang-Claude, Jenny, Chen, Sai, Connolly, Charles M., Easton, Douglas F., Feskens, Edith J. M., Gallinger, Steven, Giles, Graham G., Gunter, Marc J., Hampe, Jochen, Huyghe, Jeroen R., Hoffmeister, Michael, Hudson, Thomas J., Jacobs, Eric J., Jenkins, Mark A., Kampman, Ellen, Kang, Hyun Min, Kühn, Tilman, Küry, Sébastien, Lejbkowicz, Flavio, Le Marchand, Loic, Milne, Roger L., Li, Li, Li, Christopher I., Lindblom, Annika, Lindor, Noralane M., Martín, Vicente, McNeil, Caroline E., Melas, Marilena, Moreno, Victor, Newcomb, Polly A., Offit, Kenneth, Pharaoh, Paul D. P., Potter, John D., Qu, Chenxu, Riboli, Elio, Rennert, Gad, Sala, Núria, Schafmayer, Clemens, Scacheri, Peter C., Schmit, Stephanie L., Severi, Gianluca, Slattery, Martha L., Smith, Joshua D., Trichopoulou, Antonia, Tumino, Rosario, Ulrich, Cornelia M., van Duijnhoven, Fränzel J. B., Van Guelpen, Bethany, Weinstein, Stephanie J., White, Emily, Wolk, Alicja, Woods, Michael O., Wu, Anna H., Abecasis, Goncalo R., Casey, Graham, Nickerson, Deborah A., Gruber, Stephen B., Hsu, Li, Zheng, Wei, Peters, Ulrike
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer Berlin Heidelberg 2019
נושאים:
Original Investigation
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483948/
https://ncbi.nlm.nih.gov/pubmed/30820706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-019-01989-8
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים