Vimentin intermediate filament assembly regulates fibroblast invasion in fibrogenic lung injury

Idiopathic pulmonary fibrosis (IPF) is a progressive disease, with a median survival of 3–5 years following diagnosis. Lung remodeling by invasive fibroblasts is a hallmark of IPF. In this study, we demonstrate that inhibition of vimentin intermediate filaments (VimIFs) decreases the invasiveness of...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Surolia, Ranu, Li, Fu Jun, Wang, Zheng, Li, Huashi, Dsouza, Kevin, Thomas, Vinoy, Mirov, Sergey, Pérez-Sala, Dolores, Athar, Mohammad, Thannickal, Victor J., Antony, Veena B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2019
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483650/
https://ncbi.nlm.nih.gov/pubmed/30944258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123253
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