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Vimentin intermediate filament assembly regulates fibroblast invasion in fibrogenic lung injury
Idiopathic pulmonary fibrosis (IPF) is a progressive disease, with a median survival of 3–5 years following diagnosis. Lung remodeling by invasive fibroblasts is a hallmark of IPF. In this study, we demonstrate that inhibition of vimentin intermediate filaments (VimIFs) decreases the invasiveness of...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6483650/ https://ncbi.nlm.nih.gov/pubmed/30944258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123253 |
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