Disruption of latent HIV in vivo during the clearance of actinic keratosis by ingenol mebutate

Actinic keratosis (AK) is a precancerous skin lesion that is common in HIV-positive patients. Without effective treatment, AKs can progress to squamous cell carcinoma. Ingenol mebutate, a PKC agonist, is a US Food and Drug Administration–approved (FDA-approved) topical treatment for AKs. It can indu...

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Publicado en:JCI Insight
Autores principales: Jiang, Guochun, Maverakis, Emanual, Cheng, Michelle Y., Elsheikh, Maher M., Deleage, Claire, Méndez-Lagares, Gema, Shimoda, Michiko, Yukl, Steven A., Hartigan-O’Connor, Dennis J., Thompson, George R., Estes, Jacob D., Wong, Joseph K., Dandekar, Satya
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483647/
https://ncbi.nlm.nih.gov/pubmed/30944245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126027
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