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Platelet-derived β2M regulates monocyte inflammatory responses

β-2 Microglobulin (β2M) is a molecular chaperone for the major histocompatibility class I (MHC I) complex, hemochromatosis factor protein (HFE), and the neonatal Fc receptor (FcRn), but β2M may also have less understood chaperone-independent functions. Elevated plasma β2M has a direct role in neuroc...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Hilt, Zachary T., Pariser, Daphne N., Ture, Sara K., Mohan, Amy, Quijada, Pearl, Asante, Akua A., Cameron, Scott J., Sterling, Julie A., Merkel, Alyssa R., Johanson, Andrew L., Jenkins, Jermaine L., Small, Eric M., McGrath, Kathleen E., Palis, James, Elliott, Michael R., Morrell, Craig N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483513/
https://ncbi.nlm.nih.gov/pubmed/30702442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122943
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