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Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age

The molecular underpinnings associated with cognitive reserve remain poorly understood. Because animal models fail to fully recapitulate the complexity of human brain aging, postmortem studies from well-designed cohorts are crucial to unmask mechanisms conferring cognitive resistance against cumulat...

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Bibliographische Detailangaben
Veröffentlicht in:Neurobiol Dis
Hauptverfasser: Ramos-Miguel, Alfredo, Jones, Andrea A., Sawada, Ken, Barr, Alasdair M., Bayer, Thomas A., Falkai, Peter, Leurgans, Sue E., Schneider, Julie A., Bennett, David A., Honer, William G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483375/
https://ncbi.nlm.nih.gov/pubmed/29496544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.02.006
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