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Low genetic heterogeneity of copy number variations (CNVs) in the genes encoding the human deoxyribonucleases 1-like 3 and II potentially relevant to autoimmunity

Deoxyribonucleases (DNases) might play a role in prevention of autoimmune conditions such as systemic lupus erythematosus through clearance of cell debris resulting from apoptosis and/or necrosis. Previous studies have suggested that variations in the in vivo activities of DNases I-like 3(1L3) and I...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ueki, Misuzu, Fujihara, Junko, Kimura-Kataoka, Kaori, Yamada, Kazuo, Takinami, Yoshikazu, Takeshita, Haruo, Iida, Reiko, Yasuda, Toshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483174/
https://ncbi.nlm.nih.gov/pubmed/31022206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215479
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