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Triptolide inhibits Wnt signaling in NSCLC through upregulation of multiple Wnt inhibitory factors via epigenetic modifications to Histone H3

In the last decade, it has become clear that epigenetic changes act together with genetic mutations to promote virtually every stage of tumorigenesis and cancer progression. This knowledge has triggered searches for “epigenetic drugs” that can be developed into new cancer therapies. Here we report t...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Nardi, Isaac, Reno, Theresa, Yun, Xinwei, Sztain, Terra, Wang, Jami, Dai, Huifang, Zheng, Li, Kim, Jae, Raz, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483070/
https://ncbi.nlm.nih.gov/pubmed/30006924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31756
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