Triptolide inhibits Wnt signaling in NSCLC through upregulation of multiple Wnt inhibitory factors via epigenetic modifications to Histone H3

In the last decade, it has become clear that epigenetic changes act together with genetic mutations to promote virtually every stage of tumorigenesis and cancer progression. This knowledge has triggered searches for “epigenetic drugs” that can be developed into new cancer therapies. Here we report t...

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Udgivet i:Int J Cancer
Main Authors: Nardi, Isaac, Reno, Theresa, Yun, Xinwei, Sztain, Terra, Wang, Jami, Dai, Huifang, Zheng, Li, Kim, Jae, Raz, Dan
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483070/
https://ncbi.nlm.nih.gov/pubmed/30006924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31756
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