Adenine acts in the kidney as a signaling factor and causes salt- and water-losing nephropathy: early mechanism of adenine-induced renal injury

Chronic adenine feeding is extensively used to develop animal models of chronic renal failure with metabolic features resembling those observed in humans. However, the mechanism by which adenine induces renal failure is poorly understood. In this study, we examined the early effects of adenine on wa...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Dos Santos, Ingrid F., Sheriff, Sulaiman, Amlal, Sihame, Ahmed, Rafeeq P. H., Thakar, Charuhas V., Amlal, Hassane
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2019
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483032/
https://ncbi.nlm.nih.gov/pubmed/30623725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00142.2018
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