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Preservation of reserve intestinal epithelial stem cells following severe ischemic injury

Intestinal ischemia is an abdominal emergency with a mortality rate >50%, leading to epithelial barrier loss and subsequent sepsis. Epithelial renewal and repair after injury depend on intestinal epithelial stem cells (ISC) that reside within the crypts of Lieberkühn. Two ISC populations critical...

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Bibliografske podrobnosti
izdano v:Am J Physiol Gastrointest Liver Physiol
Main Authors: Gonzalez, Liara M., Stewart, Amy Stieler, Freund, John, Kucera, Cecilia Renee, Dekaney, Christopher M., Magness, Scott T., Blikslager, Anthony T.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483022/
https://ncbi.nlm.nih.gov/pubmed/30714814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00262.2018
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