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Preservation of reserve intestinal epithelial stem cells following severe ischemic injury

Intestinal ischemia is an abdominal emergency with a mortality rate >50%, leading to epithelial barrier loss and subsequent sepsis. Epithelial renewal and repair after injury depend on intestinal epithelial stem cells (ISC) that reside within the crypts of Lieberkühn. Two ISC populations critical...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Gonzalez, Liara M., Stewart, Amy Stieler, Freund, John, Kucera, Cecilia Renee, Dekaney, Christopher M., Magness, Scott T., Blikslager, Anthony T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483022/
https://ncbi.nlm.nih.gov/pubmed/30714814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00262.2018
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