लोड हो रहा है...
Targeting MRTF/SRF in CAP2-dependent dilated cardiomyopathy delays disease onset
About one-third of dilated cardiomyopathy (DCM) cases are caused by mutations in sarcomere or cytoskeletal proteins. However, treating the cytoskeleton directly is not possible because drugs that bind to actin are not well tolerated. Mutations in the actin binding protein CAP2 can cause DCM and KO m...
में बचाया:
| में प्रकाशित: | JCI Insight |
|---|---|
| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Clinical Investigation
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6483011/ https://ncbi.nlm.nih.gov/pubmed/30762586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124629 |
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