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Cancer stem cell–associated miRNAs serve as prognostic biomarkers in colorectal cancer

Chemoresistance in cancer is linked to a subset of cancer cells termed “cancer stem cells” (CSCs), and in particular, those expressing the CD44 variant appear to represent a more aggressive disease phenotype. Herein, we demonstrate that CD44v6 represents a CSC population with increased resistance to...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Toden, Shusuke, Kunitoshi, Shigeyasu, Cardenas, Jacob, Gu, Jinghua, Hutchins, Elizabeth, Van Keuren-Jensen, Kendall, Uetake, Hiroyuki, Toiyama, Yuji, Goel, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483002/
https://ncbi.nlm.nih.gov/pubmed/30895943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125294
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