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The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3
Human p300 is a transcriptional co-activator and a major acetyltransferase that acetylates histones and other proteins facilitating gene transcription. The activity of p300 relies on the fine-tuned interactome that involves a dozen p300 domains and hundreds of binding partners and links p300 to a wi...
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| Publicado en: | Nat Struct Mol Biol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482957/ https://ncbi.nlm.nih.gov/pubmed/30150647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0114-9 |
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